Version 5.4
Mus musculus Protein: Syt10
Summary
InnateDB Protein IDBP-174846.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Syt10
Protein Name synaptotagmin X
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000029441
InnateDB Gene IDBG-174844 (Syt10)
Protein Structure
UniProt Annotation
Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006810 transport
GO:0017158 regulation of calcium ion-dependent exocytosis
Cellular Component
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Protein Structure and Domains
PDB ID MGI:1859546
InterPro IPR000008 C2 domain
IPR001565 Synaptotagmin
PFAM PF00168
PRINTS PR00360
PR00399
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9R0N4
PhosphoSite PhosphoSite-Q9R0N4
TrEMBL Q059J3
UniProt Splice Variant
Entrez Gene 54526
UniGene Mm.261601
RefSeq NP_061273
MGI ID
MGI Symbol Syt10
OMIM
CCDS CCDS27756
HPRD
IMGT
EMBL AB026807 BC125632 BC125634 CH466550
GenPept AAI25633 AAI25635 BAA85779 EDL04326

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca