InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psmd10

Summary

InnateDB Protein

IDBP-175125.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psmd10

Protein Name

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

Synonyms

AW554874;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033805

InnateDB Gene

IDBG-175123 (Psmd10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008134	transcription factor binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006915	apoptotic process
GO:0007253	cytoplasmic sequestering of NF-kappaB
GO:0030307	positive regulation of cell growth
GO:0031398	positive regulation of protein ubiquitination
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043066	negative regulation of apoptotic process
GO:0043409	negative regulation of MAPK cascade
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0070682	proteasome regulatory particle assembly
GO:0090201	negative regulation of release of cytochrome c from mitochondria

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0008540	proteasome regulatory particle, base subcomplex
GO:0015629	actin cytoskeleton
GO:0045111	intermediate filament cytoskeleton