Version 5.4
Mus musculus Protein: Cdca4
Summary
InnateDB Protein IDBP-175168.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdca4
Protein Name cell division cycle associated 4
Synonyms 2410018C03Rik; HEPP; SEI-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000058901
InnateDB Gene IDBG-175166 (Cdca4)
Protein Structure
UniProt Annotation
Function May participate in the regulation of cell proliferation through the E2F/RB pathway (By similarity). May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed preferentially in hematopoietic progenitors and mature blood cells. Expressed at low levels in the heart, lung, spleen, and thymus and at a higher level in muscle.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1919213
InterPro IPR009263 SERTA domain
PFAM PF06031
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CWM2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 71963
UniGene Mm.465986
RefSeq NP_082299
MGI ID
MGI Symbol Cdca4
OMIM
CCDS CCDS26198
HPRD
IMGT
EMBL AF322238 AK010535 AK032980 AK156081 BC012953 BC055824
GenPept AAH12953 AAH55824 AAK31074 BAB27012 BAC28109 BAE33578

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca