Version 5.4
Mus musculus Protein: Rad18
Summary
InnateDB Protein IDBP-175184.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Rad18
Protein Name RAD18 homolog (S. cerevisiae)
Synonyms 2810024C04Rik; Rad18sc;
Species Mus musculus
Ensembl Protein ENSMUSP00000070619
InnateDB Gene IDBG-175180 (Rad18)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 34 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000403 Y-form DNA binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0031593 polyubiquitin binding
GO:0031625 ubiquitin protein ligase binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0009411 response to UV
GO:0045910 negative regulation of DNA recombination
Cellular Component
GO:0000785 chromatin
GO:0001741 XY body
GO:0005634 nucleus
GO:0005657 replication fork
Protein Structure and Domains
PDB ID MGI:1890476
InterPro IPR001841 Zinc finger, RING-type
IPR003034 SAP domain
IPR006642 Zinc finger, Rad18-type putative
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF02037
PF00097
PRINTS
PIRSF
SMART SM00184
SM00513
SM00734
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q392
UniProt Splice Variant
Entrez Gene 58186
UniGene Mm.421960
RefSeq NP_001161202
MGI ID
MGI Symbol Rad18
OMIM
CCDS CCDS51870
HPRD
IMGT
EMBL AC153591 AC157095
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca