InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sfr1

Summary

InnateDB Protein

IDBP-175313.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sfr1

Protein Name

SWI5 dependent recombination repair 1

Synonyms

6330577E15Rik; Meir5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000096954

InnateDB Gene

IDBG-175307 (Sfr1)

Protein Structure

UniProt Annotation

Function

Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. {ECO:0000269PubMed:20976249}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:20976249}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0000724

double-strand break repair via homologous recombination

Cellular Component

GO:0005634	nucleus
GO:0032798	Swi5-Sfr1 complex

Protein Structure and Domains

PDB ID

MGI:1915038

InterPro

IPR018468 Double-strand recombination repair protein, Mei5-like

PFAM

PF10376

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BP27

PhosphoSite

PhosphoSite-Q8BP27

TrEMBL

E3WH30

UniProt Splice Variant

Entrez Gene

67788

UniGene

Mm.402867

RefSeq

NP_080653

MGI ID

MGI Symbol

Sfr1

OMIM

CCDS

CCDS38019

HPRD

IMGT

EMBL

AB597963 AK004073 AK011531 AK014266 AK016079 AK077875 AK078147 AK146810 AK167406 AK168068 AK168427 BC024403

GenPept

AAH24403 BAB23154 BAB27680 BAB29232 BAB30105 BAC37045 BAC37148 BAE27450 BAE39495 BAE40043 BAE40336 BAJ25749