InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Brf1

Summary

InnateDB Protein

IDBP-175474.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Brf1

Protein Name

BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)

Synonyms

2510002F24Rik; GTF3B; mTFIIIB90; TAF3C; TAFIII90; TFIIIB90;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000011302

InnateDB Gene

IDBG-175472 (Brf1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003743	translation initiation factor activity
GO:0008270	zinc ion binding
GO:0017025	TBP-class protein binding

Biological Process

GO:0006352	DNA-templated transcription, initiation
GO:0006413	translational initiation
GO:0043488	regulation of mRNA stability
GO:0045893	positive regulation of transcription, DNA-templated

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:1919558

InterPro

IPR000812 Transcription factor TFIIB
IPR011665 Brf1-like TBP-binding
IPR013137 Zinc finger, TFIIB-type
IPR013150 Transcription factor TFIIB, cyclin-like domain
IPR013763 Cyclin-like

PFAM

PF07741
PF08271
PF00382

PRINTS

PR00685

PIRSF

SMART

SM00385

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt