Version 5.4
Mus musculus Protein: Olig1
Summary
InnateDB Protein IDBP-175838.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Olig1
Protein Name oligodendrocyte transcription factor 1
Synonyms AI836478; AW494459; Bhlhb6; bHLHe21; Olg-1; Oligo1;
Species Mus musculus
Ensembl Protein ENSMUSP00000061408
InnateDB Gene IDBG-175836 (Olig1)
Protein Structure
UniProt Annotation
Function Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube. {ECO:0000269PubMed:11955448}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.
Disease Associations
Tissue Specificity Expressed specifically in brain. {ECO:0000269PubMed:11091082}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0048663 neuron fate commitment
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:1355334
InterPro IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
PFAM PF00010
PRINTS
PIRSF
SMART SM00353
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9JKN5
PhosphoSite PhosphoSite-Q9JKN5
TrEMBL Q3UN59
UniProt Splice Variant
Entrez Gene 50914
UniGene Mm.39300
RefSeq NP_058664
MGI ID
MGI Symbol Olig1
OMIM
CCDS CCDS28324
HPRD
IMGT
EMBL AB038696 AF232928 AK144435 AK158791 BC046316
GenPept AAF61721 AAH46316 BAB18906 BAE25888 BAE34667

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca