InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psmd1

Summary

InnateDB Protein

IDBP-176432.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psmd1

Protein Name

proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

Synonyms

2410026J11Rik; P112; S1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027432

InnateDB Gene

IDBG-176430 (Psmd1)

Protein Structure

UniProt Annotation

Function

Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 98 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	98 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0030234	enzyme regulator activity

Biological Process

GO:0042176	regulation of protein catabolic process
GO:0050790	regulation of catalytic activity

Cellular Component

GO:0000502	proteasome complex
GO:0022624	proteasome accessory complex

Protein Structure and Domains

PDB ID

MGI:1917497

InterPro

IPR002015 Proteasome/cyclosome repeat
IPR016024 Armadillo-type fold
IPR016642 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit

PFAM

PF01851

PRINTS

PIRSF

PIRSF015947

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3TXS7