Version 5.4
Mus musculus Protein: Gpr89
Summary
InnateDB Protein IDBP-176551.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gpr89
Protein Name G protein-coupled receptor 89
Synonyms 4933412D19Rik; Gpr89a; SH120;
Species Mus musculus
Ensembl Protein ENSMUSP00000029738
InnateDB Gene IDBG-176549 (Gpr89)
Protein Structure
UniProt Annotation
Function Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. {ECO:0000250}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Detected at low levels in lysosomes and endosomes. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008308 voltage-gated anion channel activity
Biological Process
GO:0006811 ion transport
GO:0015031 protein transport
GO:0034765 regulation of ion transmembrane transport
GO:0043588 skin development
GO:0044070 regulation of anion transport
GO:0051452 intracellular pH reduction
Cellular Component
GO:0016021 integral component of membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID MGI:1914799
InterPro IPR022535 Golgi pH regulator, conserved domain
IPR025969 Abscisic acid G-protein coupled receptor-like domain
PFAM PF12537
PF12430
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BS95
PhosphoSite PhosphoSite-Q8BS95
TrEMBL
UniProt Splice Variant
Entrez Gene 67549
UniGene Mm.46722
RefSeq NP_080505
MGI ID
MGI Symbol Gpr89
OMIM
CCDS CCDS17650
HPRD
IMGT
EMBL AK016787 AK034895 BC010729
GenPept AAH10729 BAB30430 BAC28872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca