Version 5.4
Mus musculus Protein: Gxylt1
Summary
InnateDB Protein IDBP-176587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gxylt1
Protein Name glucoside xylosyltransferase 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000047281
InnateDB Gene IDBG-176585 (Gxylt1)
Protein Structure
UniProt Annotation
Function Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016757 transferase activity, transferring glycosyl groups
GO:0035252 UDP-xylosyltransferase activity
Biological Process
GO:0016266 O-glycan processing
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2684933
InterPro IPR002495 Glycosyl transferase, family 8
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF01501
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UHH8
PhosphoSite PhosphoSite-Q3UHH8
TrEMBL
UniProt Splice Variant
Entrez Gene 223827
UniGene Mm.474721
RefSeq NP_001028447
MGI ID
MGI Symbol Gxylt1
OMIM
CCDS CCDS27764
HPRD
IMGT
EMBL AC127360 AK147387 BC141302 BC171972 CH466550
GenPept AAI41303 AAI71972 BAE27879 EDL04286

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca