InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cartpt

Summary

InnateDB Protein

IDBP-176691.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cartpt

Protein Name

CART prepropeptide

Synonyms

Cart;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022150

InnateDB Gene

IDBG-176689 (Cartpt)

Protein Structure

UniProt Annotation

Function

Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005184	neuropeptide hormone activity
GO:0005515	protein binding

Biological Process

GO:0000186	activation of MAPKK activity
GO:0001678	cellular glucose homeostasis
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0007268	synaptic transmission
GO:0008343	adult feeding behavior
GO:0009267	cellular response to starvation
GO:0032099	negative regulation of appetite
GO:0032812	positive regulation of epinephrine secretion
GO:0032922	circadian regulation of gene expression
GO:0045671	negative regulation of osteoclast differentiation
GO:0045777	positive regulation of blood pressure
GO:0045779	negative regulation of bone resorption
GO:0046850	regulation of bone remodeling
GO:0050796	regulation of insulin secretion
GO:0051971	positive regulation of transmission of nerve impulse
GO:0070093	negative regulation of glucagon secretion
GO:0070253	somatostatin secretion