InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Etfb

Summary

InnateDB Protein

IDBP-176923.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Etfb

Protein Name

electron transferring flavoprotein, beta polypeptide

Synonyms

0610009I16Rik; 2810441H06Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004729

InnateDB Gene

IDBG-176921 (Etfb)

Protein Structure

UniProt Annotation

Function

The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0009055	electron carrier activity

Biological Process

GO:0055114

oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0017133	mitochondrial electron transfer flavoprotein complex
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:106098

InterPro

IPR012255 Electron transfer flavoprotein, beta subunit
IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal

PFAM

PF01012

PRINTS

PIRSF

PIRSF000090

SMART

SM00893

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9DCW4

PhosphoSite

PhosphoSite-Q9DCW4

TrEMBL

UniProt Splice Variant

Entrez Gene

110826

UniGene

RefSeq

NP_080971

MGI ID

MGI Symbol

Etfb

OMIM

CCDS

CCDS21171

HPRD

IMGT

EMBL

AK002407 AK150293 BC049237 BC069877

GenPept

AAH49237 AAH69877 BAB22076 BAE29447