InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Kncn

Summary

InnateDB Protein

IDBP-176955.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kncn

Protein Name

kinocilin

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095531

InnateDB Gene

IDBG-176953 (Kncn)

Protein Structure

UniProt Annotation

Function

May play a role in stabilizing dense microtubular networks or in vesicular trafficking.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Preferentially expressed in the inner ear and testis. Localizes mainly in the kinocilium of sensory cells in the inner ear. Also present in the manchette of the spermatids, a transient structure enriched in interconnected microtubules (at protein level).

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0032437	cuticular plate
GO:0036064	ciliary basal body
GO:0043025	neuronal cell body
GO:0045177	apical part of cell
GO:0060091	kinocilium