InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nmur1

Summary

InnateDB Protein

IDBP-177027.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nmur1

Protein Name

neuromedin U receptor 1

Synonyms

FM-3; Gpr66; NmU-R; NMU-R1; NMU1R;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027440

InnateDB Gene

IDBG-177025 (Nmur1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001607	neuromedin U receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0008188	neuropeptide receptor activity

Biological Process

GO:0006816	calcium ion transport
GO:0006821	chloride transport
GO:0006939	smooth muscle contraction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007202	activation of phospholipase C activity
GO:0007218	neuropeptide signaling pathway
GO:0019722	calcium-mediated signaling
GO:0048016	inositol phosphate-mediated signaling

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1341898

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR005390 Neuromedin U receptor
IPR005391 Neuromedin U receptor, type 1
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR01565
PR01566

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite