Version 5.4
Mus musculus Protein: Cd33
Summary
InnateDB Protein IDBP-177084.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd33
Protein Name CD33 antigen
Synonyms gp67; Siglec-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000004728
InnateDB Gene IDBG-177082 (Cd33)
Protein Structure
UniProt Annotation
Function Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. {ECO:0000250}.
Subcellular Localization Cell membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:99440
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q63994
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 12489
UniGene Mm.140157
RefSeq NP_001104528
MGI ID
MGI Symbol Cd33
OMIM
CCDS CCDS52224
HPRD
IMGT
EMBL BC132379 S71345 S71403
GenPept AAB30842 AAB30843 AAI32380

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca