Version 5.4
| Mus musculus Protein: Vipr2 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-177641.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Vipr2 | ||||||||
| Protein Name | vasoactive intestinal peptide receptor 2 | ||||||||
| Synonyms | Vip2; VPAC2; VPAC2R; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000011315 | ||||||||
| InnateDB Gene | IDBG-177637 (Vipr2) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. | ||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed at high levels in the MIN6 cells, at moderate levels in pancreatic islets, insulin-secreting cells, lung, brain, stomach, and colon, and at low levels in the heart. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:107166 | ||||||||
| InterPro |
IPR000832
GPCR, family 2, secretin-like IPR001571 GPCR, family 2, vasoactive intestinal peptide receptor IPR001879 GPCR, family 2, extracellular hormone receptor domain IPR002284 GPCR, family 2, vasoactive intestinal peptide receptor 2 IPR003288 GPCR, family 2, growth hormone-releasing hormone receptor IPR017981 GPCR, family 2-like |
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| PFAM |
PF00002
PF02793 |
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| PRINTS |
PR00249
PR00491 PR01155 PR01352 |
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| PIRSF | |||||||||
| SMART |
SM00008
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P41588 | ||||||||
| PhosphoSite | PhosphoSite-P41588 | ||||||||
| TrEMBL | Q546Q8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 22355 | ||||||||
| UniGene | Mm.395245 | ||||||||
| RefSeq | NP_033537 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Vipr2 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS26210 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AJ272314 AJ272315 AJ272316 AJ272317 AJ272318 AJ272319 AJ272320 AJ272321 AJ272322 AJ272323 BC138572 D28132 S82966 | ||||||||
| GenPept | AAI38573 AAN86758 BAA05674 CAC29353 | ||||||||