InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Reg4

Summary

InnateDB Protein

IDBP-177848.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Reg4

Protein Name

regenerating islet-derived family, member 4

Synonyms

2010002L15Rik; GISP; RELP;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000029469

InnateDB Gene

IDBG-177846 (Reg4)

Protein Structure

UniProt Annotation

Function

Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008201	heparin binding
GO:0030246	carbohydrate binding
GO:2001065	mannan binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:1914959

InterPro

IPR001304 C-type lectin
IPR016187 C-type lectin fold

PFAM

PF00059

PRINTS

PIRSF

SMART

SM00034

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D8G5

PhosphoSite

PhosphoSite-Q9D8G5

TrEMBL

UniProt Splice Variant

Entrez Gene

67709

UniGene

Mm.46306

RefSeq

NP_080604

MGI ID

MGI Symbol

Reg4

OMIM

CCDS

CCDS17661

HPRD

IMGT

EMBL

AK008049 AK008438 AK162316 BC019465

GenPept

AAH19465 BAB25429 BAB25669 BAE36851