Mus musculus Protein: Obscn
Summary
InnateDB Protein IDBP-177941.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Obscn
Protein Name obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000020732
InnateDB Gene IDBG-177933 (Obscn)
Protein Structure
UniProt Annotation
Function Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle (By similarity). {ECO:0000250UniProtKB:Q5VST9}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID MGI:2681862
InterPro IPR000048 IQ motif, EF-hand binding site
IPR000219 Dbl homology (DH) domain
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013151 Immunoglobulin
PFAM PF00612
PF00621
PF00018
PF14604
PF00169
PF00041
PF01108
PF07679
PF00047
PRINTS PR00452
PIRSF
SMART SM00015
SM00325
SM00326
SM00233
SM00406
SM00408
SM00409
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-A2AAJ9
TrEMBL Z4YJE4
UniProt Splice Variant
Entrez Gene 380698
UniGene Mm.339542
RefSeq
MGI ID
MGI Symbol Obscn
OMIM
CCDS
HPRD
IMGT
EMBL AL645854 AL662809
GenPept