Version 5.4
| Mus musculus Protein: Klk1b27 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-178073.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Klk1b27 | ||||||||
| Protein Name | kallikrein 1-related peptidase b27 | ||||||||
| Synonyms | Gk27; Klk21l; Klk27; mGK-27; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000078786 | ||||||||
| InnateDB Gene | IDBG-178071 (Klk1b27) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Serine protease with chymotrypsin-like cleavage specificity. Shows activity towards casein, gelatin, IGFBP3 and fibronectin but not towards laminin or collagens I and IV. Does not hydrolyze kininogin to release Lys-bradykinin. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in testis and submaxillary gland. Not expressed in heart, brain, spleen, lung, liver, muscle, kidney and ovary. In the testis, expression localized specifically to Leydig cells in the interstitial tissues. {ECO:0000269PubMed:11082197}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:891980 | ||||||||
| InterPro |
IPR001254
Peptidase S1 IPR001314 Peptidase S1A, chymotrypsin-type IPR009003 Trypsin-like cysteine/serine peptidase domain |
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| PFAM |
PF00089
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| PRINTS |
PR00722
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| PIRSF | |||||||||
| SMART |
SM00020
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9JM71 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 16619 | ||||||||
| UniGene | Mm.445911 | ||||||||
| RefSeq | NP_064664 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Klk1b27 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21194 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB039275 BC132090 BC132665 | ||||||||
| GenPept | AAI32091 AAI32666 BAA92318 | ||||||||