Version 5.4
Mus musculus Protein: Efhd1
Summary
InnateDB Protein IDBP-178083.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Efhd1
Protein Name EF hand domain containing 1
Synonyms 4931430I01Rik; AI452351; mitocalcin; PP3051;
Species Mus musculus
Ensembl Protein ENSMUSP00000027472
InnateDB Gene IDBG-178079 (Efhd1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Highest expression in testis, followed by ovary, kidney, cerebrum, cerebellum, heart, liver, and spleen. In the cerebrum and cerebellum, undetectable at embryonic stages, expression increases after birth up to adult stage. In adult CNS, detected in neurons of the cerebellum, cerebrum and hippocampus formation, including dentate gyrus and Cornu Ammonis, but not in the white matter. In the testis, expressed in spermatocytes, but not in spermatogonia nor in interstitial cells. In ovary, found predominantly in mural granulosa cells and those of the cumulus oophorus. In kidney, expressed in collecting ducts, but not in glomeruli. Not detected in skeletal muscle. {ECO:0000269PubMed:12270117}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0031175 neuron projection development
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1921607
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D4J1
PhosphoSite PhosphoSite-Q9D4J1
TrEMBL
UniProt Splice Variant
Entrez Gene 98363
UniGene Mm.399025
RefSeq NP_083165
MGI ID
MGI Symbol Efhd1
OMIM
CCDS CCDS15132
HPRD
IMGT
EMBL AK016491 AK045911 AK144175 AK171846 BC019531 BC085088
GenPept AAH19531 AAH85088 BAB30268 BAC32529 BAE25747 BAE42694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca