InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ppp3cc

Summary

InnateDB Protein

IDBP-178204.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ppp3cc

Protein Name

protein phosphatase 3, catalytic subunit, gamma isoform

Synonyms

Calnc;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000077532

InnateDB Gene

IDBG-178202 (Ppp3cc)

Protein Structure

UniProt Annotation

Function

Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.

Subcellular Localization

Disease Associations

Tissue Specificity

Testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0005516	calmodulin binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0016311

dephosphorylation

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:107162

InterPro

IPR004843 Calcineurin-like phosphoesterase domain, apaH type
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR029052 Metallo-dependent phosphatase-like

PFAM

PF00149

PRINTS

PR00114

PIRSF

SMART

SM00156

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt