Version 5.4
Mus musculus Protein: Klk1b3
Summary
InnateDB Protein IDBP-178260.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk1b3
Protein Name kallikrein 1-related peptidase b3
Synonyms mGk-3; Ngfg;
Species Mus musculus
Ensembl Protein ENSMUSP00000082577
InnateDB Gene IDBG-178258 (Klk1b3)
Protein Structure
UniProt Annotation
Function 7S NGF alpha chain stabilizes the 7S complex. The beta dimer promotes neurite growth. The gamma chain is an arginine- specific protease; it may also have plasminogen activator activity, as well as mitogenic activity for chick embryo fibroblasts.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005057 receptor signaling protein activity
GO:0008083 growth factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0035556 intracellular signal transduction
Cellular Component
Protein Structure and Domains
PDB ID MGI:97322
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P00756
PhosphoSite PhosphoSite-
TrEMBL Q9CVU2
UniProt Splice Variant
Entrez Gene 18050
UniGene Mm.439740
RefSeq NP_032719
MGI ID 1SGF
MGI Symbol Klk1b3
OMIM
CCDS CCDS21199
HPRD
IMGT
EMBL AK006516 BC132657 BC132659 X01389 X01798 X01799
GenPept AAI32658 AAI32660 BAB24629 CAA25645 CAA25928 CAA25930

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca