Version 5.4
Mus musculus Protein: Wars2
Summary
InnateDB Protein IDBP-178429.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wars2
Protein Name tryptophanyl tRNA synthetase 2 (mitochondrial)
Synonyms 5730427B17Rik; 9430020O07Rik; AI413375; TrpRS;
Species Mus musculus
Ensembl Protein ENSMUSP00000004343
InnateDB Gene IDBG-178427 (Wars2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004830 tryptophan-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0001570 vasculogenesis
GO:0006418 tRNA aminoacylation for protein translation
GO:0006436 tryptophanyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID MGI:1917810
InterPro IPR002305 Aminoacyl-tRNA synthetase, class Ic
IPR002306 Tryptophan-tRNA ligase
PFAM PF00579
PRINTS PR01039
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CYK1
PhosphoSite PhosphoSite-Q9CYK1
TrEMBL
UniProt Splice Variant
Entrez Gene 70560
UniGene Mm.404557
RefSeq NP_081738
MGI ID
MGI Symbol Wars2
OMIM
CCDS CCDS17672
HPRD
IMGT
EMBL AK017602 AK042715 AK042964 BC089583
GenPept AAH89583 BAB30833 BAC31342 BAC31422

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca