Version 5.4
Mus musculus Protein: Ripply3
Summary
InnateDB Protein IDBP-178541.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ripply3
Protein Name ripply3 homolog (zebrafish)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000023660
InnateDB Gene IDBG-178539 (Ripply3)
Protein Structure
UniProt Annotation
Function Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives. {ECO:0000269PubMed:21177346}.
Subcellular Localization Nucleus {ECO:0000250UniProtKB:Q2WG80}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
GO:0060037 pharyngeal system development
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:2181192
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q924S9
PhosphoSite PhosphoSite-Q924S9
TrEMBL
UniProt Splice Variant
Entrez Gene 170765
UniGene Mm.42604
RefSeq NP_573492
MGI ID
MGI Symbol Ripply3
OMIM
CCDS CCDS28347
HPRD
IMGT
EMBL AB063284 AK041355 AK172430 BC060291 CT573086
GenPept AAH60291 BAB60891 BAC30916 BAE43004 CAX15354

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca