InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rassf6

Summary

InnateDB Protein

IDBP-178742.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rassf6

Protein Name

Ras association (RalGDS/AF-6) domain family member 6

Synonyms

1600016B17Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031317

InnateDB Gene

IDBG-178740 (Rassf6)

Protein Structure

UniProt Annotation

Function

Involved in the induction of apoptosis. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B. {ECO:0000269PubMed:17404571}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006915	apoptotic process
GO:0007165	signal transduction
GO:0042981	regulation of apoptotic process
GO:0043065	positive regulation of apoptotic process

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1920496

InterPro

IPR000159 Ras-association
IPR011524 SARAH domain
IPR029071 Ubiquitin-related domain

PFAM

PF00788

PRINTS

PIRSF

SMART

SM00314

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q80UQ2

PhosphoSite

PhosphoSite-Q80UQ2

TrEMBL

G3X8Z9

UniProt Splice Variant

Entrez Gene

73246

UniGene

RefSeq

NP_082754

MGI ID

MGI Symbol

Rassf6

OMIM

CCDS

CCDS39142

HPRD

IMGT

EMBL

AC135240 AK005472 AK132288 BC039934 CH466617

GenPept

AAH39934 BAB24062 BAE21083 EDL05311