Version 5.4
Mus musculus Protein: Sftpc
Summary
InnateDB Protein IDBP-178805.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sftpc
Protein Name surfactant associated protein C
Synonyms Bricd6; pro-SpC; Sftp-2; Sftp2; SP-C; SP5; SPC;
Species Mus musculus
Ensembl Protein ENSMUSP00000022692
InnateDB Gene IDBG-178803 (Sftpc)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007585 respiratory gaseous exchange
GO:0007623 circadian rhythm
GO:0009725 response to hormone
GO:0009749 response to glucose
GO:0010033 response to organic substance
GO:0032496 response to lipopolysaccharide
GO:0032526 response to retinoic acid
GO:0033189 response to vitamin A
GO:0051260 protein homooligomerization
GO:0051384 response to glucocorticoid
GO:0051591 response to cAMP
GO:0055093 response to hyperoxia
GO:0070741 response to interleukin-6
GO:0070848 response to growth factor
GO:0071260 cellular response to mechanical stimulus
GO:0071732 cellular response to nitric oxide
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005771 multivesicular body
GO:0097208 alveolar lamellar body
Protein Structure and Domains
PDB ID MGI:109517
InterPro IPR001729 Surfactant-associated polypeptide
IPR007084 BRICHOS domain
IPR015091 Surfactant protein C, N-terminal propeptide
PFAM PF04089
PF08999
PRINTS
PIRSF
SMART SM00019
SM01039
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6P8P8
UniProt Splice Variant
Entrez Gene 20389
UniGene
RefSeq NP_035489
MGI ID
MGI Symbol Sftpc
OMIM
CCDS CCDS27254
HPRD
IMGT
EMBL AC122268 BC061137 CH466535
GenPept AAH61137 EDL35896

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca