Version 5.4
Mus musculus Protein: Ugt1a7c
Summary
InnateDB Protein IDBP-179167.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ugt1a7c
Protein Name UDP glucuronosyltransferase 1 family, polypeptide A7C
Synonyms UDPGT; UDPGT 1-6; UGT1-06; UGT1.6; Ugt1a6; Ugt1a7;
Species Mus musculus
Ensembl Protein ENSMUSP00000058683
InnateDB Gene IDBG-488750 (Ugt1a7c)
Protein Structure
UniProt Annotation
Function UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
Subcellular Localization Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed with highest levels detected in colon and kidney. {ECO:0000269PubMed:14672974}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015020 glucuronosyltransferase activity
GO:0016758 transferase activity, transferring hexosyl groups
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008152 metabolic process
GO:0030259 lipid glycosylation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3032636
InterPro IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235 Glycosyl transferase, family 28, C-terminal
PFAM PF00201
PF04101
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6ZQM8
PhosphoSite PhosphoSite-Q6ZQM8
TrEMBL
UniProt Splice Variant
Entrez Gene 94284
UniGene Mm.467021
RefSeq NP_964004
MGI ID
MGI Symbol Ugt1a7c
OMIM
CCDS CCDS15139
HPRD
IMGT
EMBL AK128918 AK144599 AK153157 AK165465 AY227199 BC141205 BC141206
GenPept AAI41206 AAI41207 AAP48598 BAC87656 BAE25958 BAE31767 BAE38202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca