InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ugt1a2

Summary

InnateDB Protein

IDBP-179173.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ugt1a2

Protein Name

UDP glucuronosyltransferase 1 family, polypeptide A2

Synonyms

UDPGT 1-2; Ugt1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000037258

InnateDB Gene

IDBG-488767 (Ugt1a2)

Protein Structure

UniProt Annotation

Function

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Subcellular Localization

Microsome {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in kidney. {ECO:0000269PubMed:14672974}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015020	glucuronosyltransferase activity
GO:0016758	transferase activity, transferring hexosyl groups
GO:0030246	carbohydrate binding

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0008152	metabolic process
GO:0030259	lipid glycosylation

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:3576049

InterPro

IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
IPR007235 Glycosyl transferase, family 28, C-terminal

PFAM

PF00201
PF04101

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P70691

PhosphoSite

PhosphoSite-P70691

TrEMBL

UniProt Splice Variant

Entrez Gene

22236

UniGene

Mm.467021

RefSeq

NP_038729

MGI ID

MGI Symbol

Ugt1a2

OMIM

CCDS

CCDS15141

HPRD

IMGT

EMBL

AK002629 AY227195 BC138676 BC145969 CH466520 D87866

GenPept

AAI38677 AAI45970 AAP48594 BAA13482 BAB22243 EDL40122