Version 5.4
| Mus musculus Protein: Il4i1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-179782.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Il4i1 | ||||||||
| Protein Name | interleukin 4 induced 1 | ||||||||
| Synonyms | Fig1; Fig1-ps; LAAO; LAO; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000033015 | ||||||||
| InnateDB Gene | IDBG-179780 (Il4i1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. {ECO:0000269PubMed:15383589}. | ||||||||
| Subcellular Localization | Isoform 1: Lysosome.Isoform 2: Lysosome. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Isoform 1 primarily found in immune tissues, mostly in B-lymphocytes. Isoform 2 restricted to the testis, predominantly in Sertoli cells at the periphery of the ducts, and the brain, including Purkinje cells, hippocampus and mitral cells in the olfactory bulb. No isoform 2 expression in fetal tissues. {ECO:0000269PubMed:16029492}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:109552 | ||||||||
| InterPro |
IPR001327
Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain IPR001613 Flavin amine oxidase IPR002937 Amine oxidase IPR002938 Monooxygenase, FAD-binding IPR003953 FAD binding domain IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like IPR006076 FAD dependent oxidoreductase IPR007698 Alanine dehydrogenase/PNT, NAD(H)-binding domain IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain |
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| PFAM |
PF00070
PF01593 PF01494 PF00890 PF03486 PF01266 PF01262 PF07992 |
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| PRINTS |
PR00757
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| PIRSF | |||||||||
| SMART |
SM01002
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | O09046 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 14204 | ||||||||
| UniGene | Mm.481013 | ||||||||
| RefSeq | NP_034345 | ||||||||
| MGI ID | 2I8W | ||||||||
| MGI Symbol | Il4i1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21217 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF538041 AK014297 AK133082 AK150582 AK151030 AK151171 AK152538 AK172393 AY157537 AY157538 AY161348 AY178834 AY442170 AY442343 BC115960 U70429 U70430 U89428 U89429 | ||||||||
| GenPept | AAB51353 AAB51354 AAC36534 AAC36535 AAI15961 AAM15529 AAM15530 AAO17038 AAO17039 AAO23118 AAO65453 AAS00457 BAB29253 BAE21502 BAE29676 BAE30047 BAE30174 BAE31293 BAE42981 | ||||||||