InnateDB Protein
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IDBP-179793.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hmgn1
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Protein Name
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high mobility group nucleosomal binding domain 1
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Synonyms
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HMG-14; Hmg14;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000061012
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InnateDB Gene
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IDBG-179791 (Hmgn1)
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Protein Structure
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Function |
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2. {ECO:0000269PubMed:15327773}.
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Subcellular Localization |
Nucleus. Cytoplasm {ECO:0000250}. Note=Cytoplasmic enrichment upon phosphorylation. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:96120
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InterPro |
IPR000079
High mobility group nucleosome-binding domain-containing family
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PFAM |
PF01101
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PRINTS |
PR00925
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PIRSF |
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SMART |
SM00527
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TIGRFAMs |
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Modification |
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SwissProt |
P18608
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PhosphoSite |
PhosphoSite-P18608
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
15312
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UniGene |
Mm.472169
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RefSeq |
NP_032277
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MGI ID |
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MGI Symbol |
Hmgn1
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OMIM |
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CCDS |
CCDS28353
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HPRD |
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IMGT |
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EMBL |
BC083138
BC088834
X53476
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GenPept |
AAH83138
AAH88834
CAA37569
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