Version 5.4
Mus musculus Protein: Wrb
Summary
InnateDB Protein IDBP-179808.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wrb
Protein Name tryptophan rich basic protein
Synonyms 5530402J05Rik; C030018G21Rik; Chd5;
Species Mus musculus
Ensembl Protein ENSMUSP00000023913
InnateDB Gene IDBG-179806 (Wrb)
Protein Structure
UniProt Annotation
Function Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005730 nucleolus
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2136882
InterPro IPR028945 WRB/Get1 family
PFAM PF04420
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K0D7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 71446
UniGene Mm.417596
RefSeq NP_997184
MGI ID
MGI Symbol Wrb
OMIM
CCDS CCDS28354
HPRD
IMGT
EMBL AK172079 BC031769
GenPept AAH31769 BAE42815

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca