InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ola1

Summary

InnateDB Protein

IDBP-179848.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ola1

Protein Name

Obg-like ATPase 1

Synonyms

2510025G09Rik; 2810405J23Rik; 2810409H07Rik; Gtpbp9; PTD004;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000028517

InnateDB Gene

IDBG-179846 (Ola1)

Protein Structure

UniProt Annotation

Function

Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. {ECO:0000255HAMAP- Rule:MF_03167}.

Subcellular Localization

Cytoplasm {ECO:0000255HAMAP-Rule:MF_03167}. Nucleus {ECO:0000255HAMAP-Rule:MF_03167}. Nucleus, nucleolus {ECO:0000255HAMAP-Rule:MF_03167}. Note=Predominantly cytoplasmic, shuttles between the nucleus and the cytoplasm. {ECO:0000255HAMAP-Rule:MF_03167}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0005525	GTP binding
GO:0015093	ferrous iron transmembrane transporter activity
GO:0016887	ATPase activity
GO:0043022	ribosome binding
GO:0043023	ribosomal large subunit binding
GO:0046872	metal ion binding

Biological Process

GO:0006200	ATP catabolic process
GO:0015684	ferrous iron transport

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1914309

InterPro

IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1
IPR006073 GTP binding domain
IPR011619 Ferrous iron transport protein B, N-terminal
IPR012676 TGS-like
IPR013029 Domain of unknown function DUF933
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF01926
PF02421
PF06071

PRINTS

PR00326

PIRSF

PIRSF006641

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt