Mus musculus Protein: Asb8 | |||||||
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Summary | |||||||
InnateDB Protein | IDBP-180095.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Asb8 | ||||||
Protein Name | ankyrin repeat and SOCS box-containing 8 | ||||||
Synonyms | 4930539L19Rik; AI788835; C430011H06Rik; | ||||||
Species | Mus musculus | ||||||
Ensembl Protein | ENSMUSP00000057864 | ||||||
InnateDB Gene | IDBG-180093 (Asb8) | ||||||
Protein Structure | |||||||
UniProt Annotation | |||||||
Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}. | ||||||
Subcellular Localization | Cytoplasm {ECO:0000250}. | ||||||
Disease Associations | |||||||
Tissue Specificity | |||||||
Comments | |||||||
Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||
PDB ID | MGI:1925791 | ||||||
InterPro |
IPR001496
SOCS protein, C-terminal IPR002110 Ankyrin repeat IPR020683 Ankyrin repeat-containing domain |
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PFAM |
PF07525
PF00023 PF13606 PF11929 PF12796 |
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PRINTS |
PR01415
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PIRSF | |||||||
SMART |
SM00253
SM00969 SM00248 |
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TIGRFAMs | |||||||
Post-translational Modifications | |||||||
Modification | |||||||
Cross-References | |||||||
SwissProt | Q91ZT9 | ||||||
PhosphoSite | PhosphoSite-Q91ZT9 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 78541 | ||||||
UniGene | Mm.416117 | ||||||
RefSeq | |||||||
MGI ID | |||||||
MGI Symbol | Asb8 | ||||||
OMIM | |||||||
CCDS | CCDS27787 | ||||||
HPRD | |||||||
IMGT | |||||||
EMBL | AF398969 BC025106 | ||||||
GenPept | AAH25106 AAK97491 | ||||||