InnateDB Protein
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IDBP-180181.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Atp6v0b
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Protein Name
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ATPase, H+ transporting, lysosomal V0 subunit B
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Synonyms
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2310024H13Rik; Atp6f; VMA16;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000047682
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InnateDB Gene
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IDBG-180179 (Atp6v0b)
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Protein Structure
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Function |
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
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Subcellular Localization |
Vacuole membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. {ECO:0000269PubMed:11441017}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
Accession |
GO Term |
GO:0008553
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hydrogen-exporting ATPase activity, phosphorylative mechanism
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GO:0015078
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hydrogen ion transmembrane transporter activity
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Biological Process |
GO:0015991
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ATP hydrolysis coupled proton transport
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Cellular Component |
GO:0005768
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endosome
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GO:0016021
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integral component of membrane
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GO:0016471
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vacuolar proton-transporting V-type ATPase complex
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GO:0033177
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proton-transporting two-sector ATPase complex, proton-transporting domain
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GO:0033179
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proton-transporting V-type ATPase, V0 domain
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PDB ID |
MGI:1890510
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InterPro |
IPR000245
V-ATPase proteolipid subunit
IPR002379
V-ATPase proteolipid subunit C-like domain
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PFAM |
PF00137
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PRINTS |
PR00122
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91V37
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q3U889
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UniProt Splice Variant |
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Entrez Gene |
114143
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UniGene |
Mm.408090
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RefSeq |
NP_291095
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MGI ID |
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MGI Symbol |
Atp6v0b
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OMIM |
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CCDS |
CCDS18540
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HPRD |
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IMGT |
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EMBL |
AB060654
AB060655
AF356006
AF356007
AK151847
AK152330
AK152823
AL627128
CH466552
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GenPept |
AAL02096
AAL02097
BAB61954
BAB61955
BAE30738
BAE31129
BAE31524
EDL30535
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