InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adamts6

Summary

InnateDB Protein

IDBP-180201.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Adamts6

Protein Name

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6

Synonyms

5031426K13; A930019D11Rik; ADAM-TS6; b2b1879.1Clo; b2b2029Clo; b2b2182Clo; b2b2187.1Clo; b2b2228Clo;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000064570

InnateDB Gene

IDBG-180197 (Adamts6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004222	metalloendopeptidase activity
GO:0008233	peptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0008150	biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005578	proteinaceous extracellular matrix
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:1347348

InterPro

IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR002870 Peptidase M12B, propeptide
IPR010294 ADAM-TS Spacer 1
IPR010909 PLAC
IPR013273 Peptidase M12B, ADAM-TS

PFAM

PF00090
PF01421
PF01562
PF05986
PF08686

PRINTS

PR01857

PIRSF

SMART

SM00209

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt