InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: H2-T23

Summary

InnateDB Protein

IDBP-180288.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

H2-T23

Protein Name

histocompatibility 2, T region locus 23

Synonyms

37b; 37c; H-2T23; H2-Qa1; Qa-1; Qa-1(b); Qa1; Qed-1; T18c; T18c(37); T23b; T23d;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000099739

InnateDB Gene

IDBG-180286 (H2-T23)

Protein Structure

UniProt Annotation

Function

Involved in the presentation of foreign antigens to the immune system.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0042605	peptide antigen binding

Biological Process

GO:0001916	positive regulation of T cell mediated cytotoxicity
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0006955	immune response
GO:0019882	antigen processing and presentation
GO:0048839	inner ear development

Cellular Component

GO:0005886	plasma membrane
GO:0030670	phagocytic vesicle membrane
GO:0042612	MHC class I protein complex
GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

MGI:95957

InterPro

IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein
IPR027648 MHC class I alpha chain

PFAM

PF00129
PF07654

PRINTS

PR01638

PIRSF

SMART

SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt