InnateDB Protein
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IDBP-180341.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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D6Wsu116e
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Protein Name
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DNA segment, Chr 6, Wayne State University 116, expressed
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Synonyms
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A130095H06; C530005J20Rik; D6Wsu116e;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000038983
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InnateDB Gene
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IDBG-180339 (D6Wsu116e)
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Protein Structure
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Function |
Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes (By similarity). {ECO:0000250}.
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Subcellular Localization |
Early endosome membrane {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
GO:0042147
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retrograde transport, endosome to Golgi
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Cellular Component |
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PDB ID |
MGI:106463
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6PGL7
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PhosphoSite |
PhosphoSite-Q6PGL7
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TrEMBL |
Q8BRP9
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UniProt Splice Variant |
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Entrez Gene |
28006
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UniGene |
Mm.395048
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RefSeq |
NP_080861
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MGI ID |
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MGI Symbol |
Fam21
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OMIM |
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CCDS |
CCDS20450
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HPRD |
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IMGT |
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EMBL |
AK038318
AK043764
AK122320
AK163765
BC049979
BC056942
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GenPept |
AAH49979
AAH56942
BAC29966
BAC31648
BAC65602
BAE37485
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