Version 5.4
Mus musculus Protein: Lnp
Summary
InnateDB Protein IDBP-180805.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lnp
Protein Name limb and neural patterns
Synonyms 2310011O18Rik; 4921514L11Rik; 9530051D01Rik; AI666268; Ul; ulnaless;
Species Mus musculus
Ensembl Protein ENSMUSP00000066891
InnateDB Gene IDBG-180803 (Lnp)
Protein Structure
UniProt Annotation
Function Plays a role in tubular endoplasmic reticulum network formation and maintenance (By similarity). May be involved in limb and central nervous system development. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Localizes to three-way ER tubule junctions. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in most tissues at basal level, with reinforcement in distal limb buds, genital bud, and in parts of the central nervous system. {ECO:0000269PubMed:12732147}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007596 blood coagulation
GO:0032330 regulation of chondrocyte differentiation
GO:0035115 embryonic forelimb morphogenesis
GO:0042733 embryonic digit morphogenesis
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1918115
InterPro IPR019273 Domain of unknown function DUF2296
PFAM PF10058
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TQ95
PhosphoSite PhosphoSite-Q7TQ95
TrEMBL A2ASM2
UniProt Splice Variant
Entrez Gene 69605
UniGene Mm.474773
RefSeq NP_081409
MGI ID
MGI Symbol Lnp
OMIM
CCDS CCDS16137
HPRD
IMGT
EMBL AK136506 AK173241 AL928644 AY312281 BC057961 BC060153
GenPept AAH57961 AAP76388 BAD32519 BAE23015 CAM20518

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca