InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rpp21

Summary

InnateDB Protein

IDBP-181014.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rpp21

Protein Name

ribonuclease P 21 subunit (human)

Synonyms

0610037N01Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025319

InnateDB Gene

IDBG-181012 (Rpp21)

Protein Structure

UniProt Annotation

Function

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004526	ribonuclease P activity
GO:0046872	metal ion binding

Biological Process

GO:0008033	tRNA processing
GO:0008150	biological_process
GO:0042493	response to drug
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

Cellular Component

GO:0005575	cellular_component
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

MGI:1914926

InterPro

IPR007175 RNAse P, Rpr2/Rpp21 subunit

PFAM

PF04032

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8R040

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

67676

UniGene

RefSeq

NP_080584

MGI ID

MGI Symbol

Rpp21

OMIM

CCDS

CCDS28719

HPRD

IMGT

EMBL

AJ504717 AK002780 AK003455 AY251016 BC028491

GenPept

AAH28491 AAP03887 BAB22353 BAB22800 CAD44293