Version 5.4
Mus musculus Protein: Mtx2
Summary
InnateDB Protein IDBP-181308.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtx2
Protein Name metaxin 2
Synonyms 1500012G02Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000028511
InnateDB Gene IDBG-181306 (Mtx2)
Protein Structure
UniProt Annotation
Function Involved in transport of proteins into the mitochondrion. {ECO:0000269PubMed:10381257}.
Subcellular Localization Mitochondrion outer membrane {ECO:0000269PubMed:10381257}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006626 protein targeting to mitochondrion
GO:0008150 biological_process
Cellular Component
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
Protein Structure and Domains
PDB ID MGI:1859652
InterPro IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold
IPR019564 Mitochondrial outer membrane transport complex, Sam37/metaxin
PFAM PF13098
PF13192
PF13462
PF13905
PF10568
PF11801
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88441
PhosphoSite PhosphoSite-O88441
TrEMBL
UniProt Splice Variant
Entrez Gene 53375
UniGene Mm.292613
RefSeq NP_058084
MGI ID
MGI Symbol Mtx2
OMIM
CCDS CCDS16148
HPRD
IMGT
EMBL AB041562 AF053550 AK087933 AK168000 AK169048 BC006641
GenPept AAC25104 AAH06641 BAA95046 BAC40046 BAE39989 BAE40836

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca