Version 5.4
Mus musculus Protein: Acot9
Summary
InnateDB Protein IDBP-181323.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acot9
Protein Name acyl-CoA thioesterase 9
Synonyms 0610041P13Rik; Acate2; C76421; MT-ACT48; p48; U8;
Species Mus musculus
Ensembl Protein ENSMUSP00000026324
InnateDB Gene IDBG-181321 (Acot9)
Protein Structure
UniProt Annotation
Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs.
Subcellular Localization Mitochondrion {ECO:0000305PubMed:10383425}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003986 acetyl-CoA hydrolase activity
GO:0005515 protein binding
GO:0047617 acyl-CoA hydrolase activity
Biological Process
GO:0006637 acyl-CoA metabolic process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1928939
InterPro IPR029069 HotDog domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9R0X4
PhosphoSite PhosphoSite-Q9R0X4
TrEMBL
UniProt Splice Variant
Entrez Gene 56360
UniGene Mm.401587
RefSeq NP_062710
MGI ID
MGI Symbol Acot9
OMIM
CCDS CCDS41187
HPRD
IMGT
EMBL AB028898 AJ238893 AK002892 AK009717 AK168713 AK170876 BC021763 BX005263 BX119978
GenPept AAH21763 BAA79193 BAB22437 BAB26460 BAE40555 BAE42086 CAB45192 CAM21953 CAM23138

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca