Version 5.4
Mus musculus Protein: Asb1
Summary
InnateDB Protein IDBP-181461.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Asb1
Protein Name ankyrin repeat and SOCS box-containing 1
Synonyms 1700029O08Rik; 1700054C17Rik; AI426616; AI851378; mKIAA1146;
Species Mus musculus
Ensembl Protein ENSMUSP00000027538
InnateDB Gene IDBG-181459 (Asb1)
Protein Structure
UniProt Annotation
Function May play a role in testis development. Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin- SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Highest expression in testis, spleen, bone marrow and salivary gland. {ECO:0000269PubMed:11111040, ECO:0000269PubMed:11509662}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0016567 protein ubiquitination
GO:0030539 male genitalia development
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1929735
InterPro IPR001496 SOCS protein, C-terminal
PFAM PF07525
PRINTS
PIRSF
SMART SM00253
SM00969
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WV74
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 65247
UniGene Mm.409514
RefSeq XP_006529852
MGI ID
MGI Symbol Asb1
OMIM
CCDS
HPRD
IMGT
EMBL AF155352
GenPept AAD38808

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca