InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nufip1

Summary

InnateDB Protein

IDBP-181468.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nufip1

Protein Name

nuclear fragile X mental retardation protein interacting protein 1

Synonyms

Nufip;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000022586

InnateDB Gene

IDBG-181466 (Nufip1)

Protein Structure

UniProt Annotation

Function

Binds RNA. {ECO:0000269PubMed:10556305}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:10556305}. Note=Distributed in the nucleus in a dot-like pattern.

Disease Associations

Tissue Specificity

Expressed in the brain; in neurons and not in glial cells. {ECO:0000269PubMed:10556305}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030515	snoRNA binding
GO:0030674	protein binding, bridging
GO:0042802	identical protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000492	box C/D snoRNP assembly
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005726	perichromatin fibrils
GO:0005730	nucleolus
GO:0008023	transcription elongation factor complex
GO:0016363	nuclear matrix
GO:0022626	cytosolic ribosome
GO:0048786	presynaptic active zone
GO:0070761	pre-snoRNP complex

Protein Structure and Domains

PDB ID

MGI:1351474

InterPro

IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR019496 Nuclear fragile X mental retardation-interacting protein 1, conserved domain
IPR022755 Zinc finger, double-stranded RNA binding

PFAM

PF00096
PF10453
PF12171

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9QXX8