Version 5.4
Mus musculus Protein: Ptchd1
Summary
InnateDB Protein IDBP-181496.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptchd1
Protein Name patched domain containing 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000039443
InnateDB Gene IDBG-181494 (Ptchd1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity Broadly expressed in the brain, with highest density in the cerebellum. {ECO:0000269PubMed:20844286}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008158 hedgehog receptor activity
Biological Process
GO:0007224 smoothened signaling pathway
GO:0050890 cognition
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2685233
InterPro IPR000731 Sterol-sensing domain
IPR003392 Patched
PFAM PF02460
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14B62
PhosphoSite PhosphoSite-Q14B62
TrEMBL
UniProt Splice Variant
Entrez Gene 211612
UniGene Mm.218811
RefSeq NP_001087219
MGI ID
MGI Symbol Ptchd1
OMIM
CCDS CCDS41188
HPRD
IMGT
EMBL AK036111 BC116312 BC116313 BX088539 BX119953
GenPept AAI16313 AAI16314 BAC29308 CAM15552 CAM20498

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca