Version 5.4
Mus musculus Protein: Cacul1
Summary
InnateDB Protein IDBP-181539.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cacul1
Protein Name RIKEN cDNA 2700078E11 gene
Synonyms 2700078E11Rik; 2810417M16Rik; 9830127L17Rik; AI450346; D130033C15Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000080480
InnateDB Gene IDBG-181537 (Cacul1)
Protein Structure
UniProt Annotation
Function Cell cycle associated protein capable of promoting cell proliferation through the activation of CDK2 at the G1/S phase transition. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008284 positive regulation of cell proliferation
GO:0045860 positive regulation of protein kinase activity
Cellular Component
GO:0005575 cellular_component
GO:0031461 cullin-RING ubiquitin ligase complex
Protein Structure and Domains
PDB ID MGI:1926082
InterPro IPR001373 Cullin, N-terminal
IPR016159 Cullin repeat-like-containing domain
PFAM PF00888
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R0X2
PhosphoSite PhosphoSite-Q8R0X2
TrEMBL Q3TAW5
UniProt Splice Variant
Entrez Gene 78832
UniGene Mm.471362
RefSeq NP_084473
MGI ID
MGI Symbol Cacul1
OMIM
CCDS CCDS38034
HPRD
IMGT
EMBL AK019216 AK147382 AK169791 AK171596 BC026363
GenPept AAH26363 BAB31607 BAE27876 BAE41369 BAE42551

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca