Version 5.4
Mus musculus Protein: Mt4
Summary
InnateDB Protein IDBP-181614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mt4
Protein Name metallothionein 4
Synonyms MT-IV;
Species Mus musculus
Ensembl Protein ENSMUSP00000034207
InnateDB Gene IDBG-181612 (Mt4)
Protein Structure
UniProt Annotation
Function Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed exclusively in stratified squamous epithelia associated with oral epithelia, esophagus, upper stomach, tail, footpads and neonatal skin.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006875 cellular metal ion homeostasis
GO:0046686 response to cadmium ion
Cellular Component
Protein Structure and Domains
PDB ID MGI:99692
InterPro IPR000006 Metallothionein, vertebrate
IPR003019 Metallothionein superfamily, eukaryotic
IPR017854 Metallothionein domain
PFAM PF00131
PRINTS PR00860
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P47945
PhosphoSite PhosphoSite-
TrEMBL Q499L1
UniProt Splice Variant
Entrez Gene 17752
UniGene Mm.1536
RefSeq NP_032657
MGI ID
MGI Symbol Mt4
OMIM
CCDS CCDS40435
HPRD
IMGT
EMBL AK131894 BC099850 BC099851 BC099852 BC099853 BC111805 BC141870 CH466525 U07808
GenPept AAA20233 AAH99850 AAH99851 AAH99852 AAH99853 AAI11806 AAI41871 BAE20856 EDL11116

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca