InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mt1

Summary

InnateDB Protein

IDBP-181687.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mt1

Protein Name

metallothionein 1

Synonyms

Mt-1; MT-I;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034215

InnateDB Gene

IDBG-181685 (Mt1)

Protein Structure

UniProt Annotation

Function

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005507	copper ion binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0006875	cellular metal ion homeostasis
GO:0006882	cellular zinc ion homeostasis
GO:0007263	nitric oxide mediated signal transduction
GO:0010273	detoxification of copper ion
GO:0043524	negative regulation of neuron apoptotic process
GO:0045926	negative regulation of growth
GO:0071247	cellular response to chromate
GO:0071294	cellular response to zinc ion