Version 5.4
Mus musculus Protein: Yy2
Summary
InnateDB Protein IDBP-181728.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Yy2
Protein Name Yy2 transcription factor
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000070112
InnateDB Gene IDBG-606464 (Yy2)
Protein Structure
UniProt Annotation
Function Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation. {ECO:0000269PubMed:17478514}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Weakly expressed by neuronal and glial cells in the cerebral cortex. Expressed by Purkinje cells and in the granular layers of the cerebellum. Expressed in all layers of spermatocytes in testis but not detected in sperm cells. {ECO:0000269PubMed:16377127}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:3837947
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR017114 Transcription factor yin/yang
PFAM PF00096
PRINTS
PIRSF PIRSF037113
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3TTC2
PhosphoSite PhosphoSite-Q3TTC2
TrEMBL
UniProt Splice Variant
Entrez Gene 100073351
UniGene
RefSeq NP_001092193
MGI ID
MGI Symbol Yy2
OMIM
CCDS CCDS53233
HPRD
IMGT
EMBL AK036071 AK161451 EF688658
GenPept ABS18955 BAC29297 BAE36403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca