InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Shmt1

Summary

InnateDB Protein

IDBP-181788.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Shmt1

Protein Name

serine hydroxymethyltransferase 1 (soluble)

Synonyms

AI324848; AI385541; C81125; mshmt; mshmt1; mshmt2; Shmt;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000018744

InnateDB Gene

IDBG-181786 (Shmt1)

Protein Structure

UniProt Annotation

Function

Interconversion of serine and glycine.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004372	glycine hydroxymethyltransferase activity
GO:0008732	L-allo-threonine aldolase activity
GO:0016597	amino acid binding
GO:0030170	pyridoxal phosphate binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0006544	glycine metabolic process
GO:0006545	glycine biosynthetic process
GO:0006563	L-serine metabolic process
GO:0006565	L-serine catabolic process
GO:0009113	purine nucleobase biosynthetic process
GO:0019264	glycine biosynthetic process from serine
GO:0035999	tetrahydrofolate interconversion
GO:0046655	folic acid metabolic process
GO:0051262	protein tetramerization
GO:0051289	protein homotetramerization