Mus musculus Protein: Ap4b1
Summary
InnateDB Protein IDBP-181813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ap4b1
Protein Name adaptor-related protein complex AP-4, beta 1
Synonyms 1810038H16Rik; Ap4b4; AV004952;
Species Mus musculus
Ensembl Protein ENSMUSP00000044262
InnateDB Gene IDBG-181809 (Ap4b1)
Protein Structure
UniProt Annotation
Function Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. {ECO:0000250}.
Subcellular Localization Golgi apparatus, trans-Golgi network {ECO:0000250}. Membrane, coated pit {ECO:0000250}. Note=Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0008565 protein transporter activity
Biological Process
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0005905 coated pit
GO:0030117 membrane coat
GO:0030131 clathrin adaptor complex
Protein Structure and Domains
PDB ID MGI:1337130
InterPro IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
IPR009028 Coatomer/calthrin adaptor appendage, C-terminal subdomain
IPR015151 Beta-adaptin appendage, C-terminal subdomain
IPR016024 Armadillo-type fold
IPR016342 AP-1, 2,4 complex subunit beta
PFAM PF01602
PF09066
PRINTS
PIRSF PIRSF002291
SMART SM01020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WV76
PhosphoSite PhosphoSite-Q9WV76
TrEMBL Q9CW72
UniProt Splice Variant
Entrez Gene 67489
UniGene Mm.197568
RefSeq NP_080469
MGI ID
MGI Symbol Ap4b1
OMIM
CCDS CCDS17696
HPRD
IMGT
EMBL AC124698 AF155157 AK003021 CU210953
GenPept AAD43327 BAB22515 CAQ12171